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Bassoon anticorps (AA 786-1041) (Atto 488)

BSN Reactivité: Humain IHC, WB Hôte: Lapin Polyclonal Atto 488
N° du produit ABIN2484533
  • Antigène Voir toutes Bassoon (BSN) Anticorps
    Bassoon (BSN)
    Épitope
    • 12
    • 2
    • 2
    • 1
    AA 786-1041
    Reactivité
    • 24
    • 14
    • 14
    • 1
    • 1
    Humain
    Hôte
    • 24
    • 3
    Lapin
    Clonalité
    • 24
    • 3
    Polyclonal
    Conjugué
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Bassoon est conjugé à/à la Atto 488
    Application
    • 19
    • 17
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Specificité
    Detects ~420 kDa. Multiple isoforms can be detected.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein A Purified
    Immunogène
    NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
    Top Product
    Discover our top product BSN Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • IHC (1:400)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN2484533 was sufficient for detection of Bassoon in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    Bassoon (BSN)
    Autre désignation
    Bassoon (BSN Produits)
    Synonymes
    anticorps Znf231, anticorps ZNF231, anticorps bassoon, anticorps bassoon (presynaptic cytomatrix protein), anticorps bassoon presynaptic cytomatrix protein, anticorps Bsn, anticorps BSN
    Sujet
    Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors (1).
    ID gène
    8927
    NCBI Accession
    NP_003449
    UniProt
    Q9UPA5
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