Bassoon anticorps (AA 786-1041) (PE)
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- Antigène Voir toutes Bassoon (BSN) Anticorps
- Bassoon (BSN)
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Épitope
- AA 786-1041
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Bassoon est conjugé à/à la PE
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Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Specificité
- Detects ~420 kDa. Multiple isoforms can be detected.
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Protein A Purified
- Immunogène
- NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
- Top Product
- Discover our top product BSN Anticorps primaire
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- Indications d'application
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- WB (1:1000)
- IHC (1:400)
- optimal dilutions for assays should be determined by the user.
- Commentaires
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1 μg/ml of ABIN2484547 was sufficient for detection of Bassoon in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- Antigène
- Bassoon (BSN)
- Autre désignation
- Bassoon (BSN Produits)
- Synonymes
- anticorps Znf231, anticorps ZNF231, anticorps bassoon, anticorps bassoon (presynaptic cytomatrix protein), anticorps bassoon presynaptic cytomatrix protein, anticorps Bsn, anticorps BSN
- Sujet
- Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors (1).
- ID gène
- 8927
- NCBI Accession
- NP_003449
- UniProt
- Q9UPA5
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