ATP7B anticorps (AA 3-21) (PE)
-
- Antigène Voir toutes ATP7B Anticorps
- ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
-
Épitope
- AA 3-21
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp ATP7B est conjugé à/à la PE
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Specificité
- Detects ~160 kDa in rat brain membrane preparations.
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Protein G Purified
- Immunogène
- Synthetic peptide amino acids 3-21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2
- Clone
- S62-29
- Isotype
- IgG1
- Top Product
- Discover our top product ATP7B Anticorps primaire
-
-
- Indications d'application
-
- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Commentaires
-
1 μg/ml of ABIN2485179 was sufficient for detection of Copper-transporting ATPase2 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Conjugated antibodies should be stored at 4°C
-
- Antigène
- ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
- Autre désignation
- ATP7B (ATP7B Produits)
- Synonymes
- anticorps PWD, anticorps WC1, anticorps WD, anticorps WND, anticorps Atp7a, anticorps tx, anticorps Hts, anticorps PINA, anticorps Wd, anticorps ATP7B, anticorps ATPase copper transporting beta, anticorps ATPase, Cu++ transporting, beta polypeptide, anticorps ATPase, Cu++ transporting, beta polypeptide (Wilson disease), anticorps copper-transporting ATPase 2, anticorps ATP7B, anticorps Atp7b, anticorps atp7b, anticorps LOC592143
- Sujet
- The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene, A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage.
- ID gène
- 540
- NCBI Accession
- NP_000044
- UniProt
- B7ZLR4
- Pathways
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
-