NPAS4 anticorps (AA 597-802)

N° du produit ABIN2485806

Détail du produit anti-NPAS4 anticorps

Antigène: NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))

Épitope: AA 597-802

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NPAS4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Highly expressed in the brain, with lower expression found in endocrine tissue.,Detects ~90 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Fusion protein amino acids 597-802 (C-terminus) of rat Npas4.

Clone: S408-79

Isotype: IgG1

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF(1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

A 1:100 dilution of ABIN2485806 was sufficient for detection of NPAS4 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur NPAS4

Antigène: NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))

Autre désignation: NPAS4 (NPAS4 Produits)

Synonymes: anticorps LE-PAS, anticorps Nxf, anticorps Le-PAS, anticorps NXF, anticorps PASD10, anticorps bHLHe79, anticorps npas4, anticorps wu:fj52d04, anticorps zgc:136764, anticorps MGC146621, anticorps neuronal PAS domain protein 4, anticorps neuronal PAS domain protein 4a, anticorps neuronal PAS domain-containing protein 4, anticorps Npas4, anticorps NPAS4, anticorps npas4a, anticorps npas4, anticorps Tsp_02837

Sujet: NPAS4 belongs to the Per-Arnt-Sim family of neuronal specific transciption factors, all involved in the development and maintenance of learning and memory pathways (1). NPAS4 is a transcription factor that regulates the formation and maintenance of inhibitory synapses, and can activate the CNS midline enhancer element and the expression of the drebrin gene. Deregulation has been to be associated with developmental disorders such as schizophrenia and autism (2).

ID gène: 266734

NCBI Accession: NP_705890

UniProt: Q8CJH6