Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2) (AA 911-929) anticorps (FITC)
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- Antigène Voir toutes Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2) Anticorps
- Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2)
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Épitope
- AA 911-929
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- FITC
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Specificité
- Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney. Isoform 3 and isoform 4 are expressed in both the inner and outer renal medulla.,Detects ~97 and 127 kDa.
- Réactivité croisée
- Souris, Rat
- Purification
- Peptide Affinity Purified
- Immunogène
- Produced against a synthetic peptide mapped to the C-terminal tail (amino acids 911-929) of rat UT-A1 (antibody designation L194)
- Top Product
- Discover our top product SLC14A2 Anticorps primaire
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- Indications d'application
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- WB (1:1000)
- IHC (1:25)
- optimal dilutions for assays should be determined by the user.
- Commentaires
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1 μg/ml of ABIN2486310 was sufficient for detection of UT-A1 in 20 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- Antigène
- Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2)
- Autre désignation
- UT-A1 (SLC14A2 Produits)
- Synonymes
- anticorps HUT2, anticorps UT-A2, anticorps UT2, anticorps UTA, anticorps UTR, anticorps hUT-A6, anticorps Slc14a2T, anticorps Slc14a2_v4, anticorps UrT1-C, anticorps UrT1-D, anticorps testSymbol, anticorps UT-A1, anticorps UT-A3, anticorps solute carrier family 14 member 2, anticorps solute carrier family 14 (urea transporter), member 2, anticorps SLC14A2, anticorps Slc14a2
- Sujet
- UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promoter and expressed in the thin descending limb of Henle, viz. UT-A2) (1, 2).
- ID gène
- 54302
- NCBI Accession
- NP_062220
- UniProt
- Q62668
- Pathways
- Response to Water Deprivation
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