DHRS2 anticorps (AA 61-160)

N° du produit ABIN2559682

Détail du produit anti-DHRS2 anticorps

Antigène: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Épitope: AA 61-160

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHRS2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DHRS2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DHRS2

Antigène: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Autre désignation: DHRS2 (DHRS2 Produits)

Synonymes: anticorps DHRS2, anticorps HEP27, anticorps SDR25C1, anticorps 5430405K24Rik, anticorps Hep27, anticorps dehydrogenase/reductase 4, anticorps dehydrogenase/reductase 2, anticorps dehydrogenase/reductase member 2, anticorps DHRS4, anticorps DHRS2, anticorps Dhrs2

Sujet:

Synonyms: HEP27, SDR25C1, Dehydrogenase/reductase SDR family member 2, mitochondrial, Dicarbonyl reductase HEP27, Protein D, DHRS2

Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

ID gène: 10202

UniProt: Q13268

Pathways: C21-Steroid Hormone Metabolic Process