Leptin Receptor anticorps (AA 901-1000) (PE)

N° du produit ABIN2559727

Détail du produit anti-Leptin Receptor anticorps (PE)

Antigène: Leptin Receptor (LEPR)

Épitope: AA 901-1000

Reactivité: Humain, Souris, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Leptin Receptor est conjugé à/à la PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Specificité: This antibody will recognize the Isoform B variant only

Réactivité croisée: Humain, Souris, Porc, Rat

Homologie: Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Leptin receptor:901-1000/1165

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Leptin Receptor (PE) (ABIN2559727)

Goto, Kaneko, Sato, Otsuka, Yamamoto, Goto, Yamamoto, Yamamoto, Kawachi, Madaio, Narita: "Leptin deficiency down-regulates IL-23 production in glomerular podocytes resulting in an attenuated immune response in nephrotoxic serum nephritis." dans: International immunology, Vol. 28, Issue 4, pp. 197-208, (2016) (PubMed).

Détails sur Leptin Receptor

Antigène: Leptin Receptor (LEPR)

Autre désignation: Leptin receptor (Isoform B) (LEPR Produits)

Synonymes: anticorps CD295, anticorps LEP-R, anticorps LEPRD, anticorps OB-R, anticorps OBR, anticorps obr, anticorps cd295, anticorps ob-rb, anticorps Fa, anticorps LEPROT, anticorps Leprb, anticorps Modb1, anticorps OB-RGRP, anticorps Obr, anticorps db, anticorps diabetes, anticorps obese-like, anticorps obl, anticorps ObRb, anticorps Ob-R, anticorps Ob-RM, anticorps lepr, anticorps leptin receptor, anticorps leptin receptor S homeolog, anticorps LEPR, anticorps lepr, anticorps Lepr, anticorps lepr.S

Sujet:

Synonyms: OBR, OB-R, CD295, LEP-R, LEPRD, Leptin receptor, HuB219, OB receptor, LEPR, DB, LEPR_MOUSE

Background: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).

ID gène: 3953

UniProt: P48357

Pathways: Signalistation JAK/STAT, AMPK Signaling, Feeding Behaviour