CD11b anticorps (PE-Cy7)
-
- Antigène Voir toutes CD11b (ITGAM) Anticorps
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
-
Reactivité
- Humain, Souris
-
Hôte
- Rat
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp CD11b est conjugé à/à la PE-Cy7
-
Application
- Flow Cytometry (FACS)
- Specificité
- The M1/70 monoclonal antibody specifically reacts with the 170 kDa αM integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18).
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Clone
- M1-70
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product ITGAM Anticorps primaire
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Stock
- 4 °C
- Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
-
- Antigène
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Autre désignation
- CD11b (ITGAM Produits)
- Synonymes
- anticorps CD11b/CD18, anticorps CR3, anticorps CR3A, anticorps Cd11b, anticorps F730045J24Rik, anticorps Ly-40, anticorps MAC1, anticorps Mac-1, anticorps Mac-1a, anticorps CD11B, anticorps MAC-1, anticorps MAC1A, anticorps MO1A, anticorps SLEB6, anticorps C3bi, anticorps integrin subunit alpha M, anticorps integrin alpha M, anticorps integrin, alpha M (complement component 3 receptor 3 subunit), anticorps integrin alpha-M, anticorps ITGAM, anticorps Itgam, anticorps LOC100351865
- Sujet
- The M1/70 monoclonal antibody specifically reacts with the 170 kDa αM integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood.M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b.
- ID gène
- 3684
- UniProt
- P11215
- Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
-