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CD11b anticorps (PE-Cy7)

ITGAM Reactivité: Humain, Souris FACS Hôte: Rat Monoclonal M1-70 PE-Cy7
N° du produit ABIN2567153
  • Antigène Voir toutes CD11b (ITGAM) Anticorps
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivité
    • 274
    • 173
    • 68
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    Humain, Souris
    Hôte
    • 152
    • 113
    • 104
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    • 1
    • 1
    Rat
    Clonalité
    • 274
    • 96
    • 1
    Monoclonal
    Conjugué
    • 117
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    Cet anticorp CD11b est conjugé à/à la PE-Cy7
    Application
    • 276
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    Flow Cytometry (FACS)
    Specificité
    The M1/70 monoclonal antibody specifically reacts with the 170 kDa αM integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18).
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Clone
    M1-70
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product ITGAM Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Stock
    4 °C
    Stockage commentaire
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Antigène
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Autre désignation
    CD11b (ITGAM Produits)
    Synonymes
    anticorps CD11b/CD18, anticorps CR3, anticorps CR3A, anticorps Cd11b, anticorps F730045J24Rik, anticorps Ly-40, anticorps MAC1, anticorps Mac-1, anticorps Mac-1a, anticorps CD11B, anticorps MAC-1, anticorps MAC1A, anticorps MO1A, anticorps SLEB6, anticorps C3bi, anticorps integrin subunit alpha M, anticorps integrin alpha M, anticorps integrin, alpha M (complement component 3 receptor 3 subunit), anticorps integrin alpha-M, anticorps ITGAM, anticorps Itgam, anticorps LOC100351865
    Sujet
    The M1/70 monoclonal antibody specifically reacts with the 170 kDa αM integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood.M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b.
    ID gène
    3684
    UniProt
    P11215
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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