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CD3 epsilon anticorps (PE-Cy5)
CD3E
Reactivité: Souris
FACS
Hôte: Hamster
Monoclonal
145-2C11
PE-Cy5
N° du produit ABIN2567608
Détail du produit anti-CD3 epsilon anticorps (PE-Cy5)
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Antigène
Voir toutes CD3 epsilon (CD3E) Anticorps
CD3 epsilon (CD3E)
Reactivité
Toutes les réactivités sur CD3 epsilon Anticorps
Souris
Hôte
Toutes les hôtes sur CD3 epsilon Anticorps
Hamster
Clonalité
Toutes les clonalités sur CD3 epsilon Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CD3 epsilon Anticorps
Cet anticorp CD3 epsilon est conjugé à/à la PE-Cy5
Application
Tous les applications à travers CD3 epsilon Anticorps.
Flow Cytometry (FACS)
Specificité
The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clone
145-2C11
Isotype
IgG
Top Product
Discover our top product CD3E Anticorps primaire
Alternatives
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anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibody
CD3E
Reactivité: Humain, Rat, Porc, Lapin, Boeuf (Vache), Cheval, Cobaye, Poulet
FACS, WB, IF
Hôte: Souris
Monoclonal
PC3-188A
unconjugated
Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.2 mg/mL
Buffer
Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Stock
4 °C
Stockage commentaire
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Détails sur CD3 epsilon
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Antigène
CD3 epsilon (CD3E)
Autre désignation
CD3e (CD3E Produits )
Synonymes
anticorps cd3e, anticorps CD3E, anticorps t3e, anticorps tcre, anticorps AI504783, anticorps CD3, anticorps CD3epsilon, anticorps T3e, anticorps T3E, anticorps TCRE, anticorps CD3e molecule, anticorps CD3 antigen, epsilon polypeptide, anticorps cd3e, anticorps CD3E, anticorps Cd3e
Sujet
The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.
ID gène
12501
UniProt
P22646
Pathways
TCR Signaling , CXCR4-mediated Signaling Events , Ubiquitin Proteasome Pathway
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