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IZUMO1 anticorps
IZUMO1
Reactivité: Humain
ELISA, WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2568277
Détail du produit anti-IZUMO1 anticorps
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Antigène
Voir toutes IZUMO1 Anticorps
IZUMO1
(Izumo Sperm-Egg Fusion 1 (IZUMO1))
Reactivité
Toutes les réactivités sur IZUMO1 Anticorps
Humain
Hôte
Toutes les hôtes sur IZUMO1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur IZUMO1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers IZUMO1 Anticorps
Cet anticorp IZUMO1 est non-conjugé
Application
Tous les applications à travers IZUMO1 Anticorps.
ELISA, Western Blotting (WB)
Specificité
IZUMO1 antibody is human specific. At least four isoforms of IZUMO1 are known to exist, this antibody will detect the two longest isoforms.
Purification
IZUMO1 antibody is affinity chromatography purified via peptide column.
Immunogène
IZUMO1 antibody was raised against an 18 amino acid peptide near the center of human IZUMO1
Isotype
IgG
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Information d'application
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Indications d'application
IZUMO1 antibody can be used for detection of IZUMO1 by Western blot at 1 - 2 μ,g/mL.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
IZUMO1 antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
IZUMO1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Détails sur IZUMO1
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Antigène
IZUMO1
(Izumo Sperm-Egg Fusion 1 (IZUMO1))
Autre désignation
IZUMO1 (IZUMO1 Produits )
Synonymes
anticorps IZUMO, anticorps 1700058F15Rik, anticorps Izumo, anticorps izumo sperm-egg fusion 1, anticorps Ras interacting protein 1, anticorps IZUMO1, anticorps RASIP1, anticorps Izumo1
Sujet
IZUMO1, a sperm-specific protein, is essential for sperm-egg plasma membrane binding and fusion. It is involved in the fertilization process and in the fusion of the sperm with the egg (1,2). IZUMO1 is expressed as at least four isoforms produced by alternative splicing and contains one Ig-like (immunoglobulin-like) C2-type domain (3). Lack of IZUMO1 in males, due to homozygous mutation in the gene that encodes IZUMO1, results in sterility due to an inability to penetrate the plasma membrane of the egg (4).
Poids moléculaire
Predicted: 35, 39, 42 kDa Observed: 52 kDa
ID gène
284359
NCBI Accession
NP_872381
UniProt
Q8IYV9
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