UBAP2L antibody is human and mouse reactive. At least four isoforms of UBAP2L are known to exist, this antibody will detect all four isoforms. This antibody is predicted to not cross-react with UBAP2.
Purification
UBAP2L Antibody is affinity chromatography purified via peptide column.
Immunogène
UBAP2L antibody was raised against a 19 amino acid peptide from near the amino terminus of human UBAP2L.
The UBA domain-containing protein ubiquitin associated protein 2-like (UBAP2L), also known as NICE4, is a ubiquitously expressed 1,087 amino acid protein. UBAP2L is preferentially expressed in hematopoietic stem cell (HSC) populations and interacts with BMI1, a well-known determinant of HSC function (1). It is essential for the activity of long-term repopulating HSCs but not the BMI1-dependent repression of the Ink4a/Arf locus (1).