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Retinoblastoma 1 anticorps (AA 393-572, AA 622-645)
RB1
Reactivité: Humain, Souris, Rat, Poulet, Vison
WB, IP
Hôte: Souris
Monoclonal
XZ91
unconjugated
Détail du produit anti-Retinoblastoma 1 anticorps
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Antigène
Voir toutes Retinoblastoma 1 (RB1) Anticorps
Retinoblastoma 1 (RB1)
Épitope
Tous les épitopes à travers Retinoblastoma 1 Anticorps.
AA 393-572, AA 622-645
Reactivité
Toutes les réactivités sur Retinoblastoma 1 Anticorps
Humain, Souris, Rat, Poulet, Vison
Hôte
Toutes les hôtes sur Retinoblastoma 1 Anticorps
Souris
Clonalité
Toutes les clonalités sur Retinoblastoma 1 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers Retinoblastoma 1 Anticorps
Cet anticorp Retinoblastoma 1 est non-conjugé
Application
Tous les applications à travers Retinoblastoma 1 Anticorps.
Western Blotting (WB), Immunoprecipitation (IP)
Specificité
Recognizes Retinoblastoma (Rb).
Attributs du produit
Synonyms: Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC
Purification
Purified
Immunogène
Recombinant protein corresponding to amino acids 393-572 of the Human Retinoblastomasequence. Remarks: The epitope is contained within amino acids 622-645 of Humanretinoblastoma.
Clone
XZ91
Isotype
IgG1
Top Product
Discover our top product RB1 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Western Blot. Immunoprecipitation. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Buffer
PBS containing 0.08 % Sodium Azide as preservative.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store the antibody (in aliquots) at -20 °C. Can be shipped at 2-8 °C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Date de péremption
12 months
Détails sur Retinoblastoma 1
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Antigène
Retinoblastoma 1 (RB1)
Autre désignation
Retinoblastoma-Associated Protein / RB1 (RB1 Produits )
Synonymes
anticorps OSRC, anticorps RB, anticorps p105-Rb, anticorps pRb, anticorps pp110, anticorps Rb, anticorps Rb-1, anticorps P105-RB, anticorps PP110, anticorps RB11, anticorps zgc:154147, anticorps RB transcriptional corepressor 1, anticorps RB transcriptional corepressor like 1, anticorps retinoblastoma 1, anticorps RB1, anticorps RBL1, anticorps Rb1, anticorps rb1
Sujet
Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110
ID gène
5925
UniProt
P06400
Pathways
Cycle Cellulaire , Intracellular Steroid Hormone Receptor Signaling Pathway , Mitotic G1-G1/S Phases , DNA Replication , Maintenance of Protein Location , Synthesis of DNA , Autophagy
Vus récemment
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