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Calpain anticorps (Agarose Beads)

Reactivité: Humain IP Hôte: Souris Monoclonal 28F3 Agarose Beads
N° du produit ABIN264386
  • Antigène Tous les produits Calpain
    Calpain
    Reactivité
    • 4
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 4
    • 3
    Souris
    Clonalité
    • 4
    • 3
    Monoclonal
    Conjugué
    • 5
    • 1
    • 1
    Cet anticorp Calpain est conjugé à/à la Agarose Beads
    Application
    • 7
    • 4
    • 3
    • 1
    • 1
    Immunoprecipitation (IP)
    Attributs du produit
    Synonyms: CAPN2, CANPL2, CANP-2, CAPN1, CANPL1, CANP1
    Purification
    Standard chromatographic techniques.
    Immunogène
    Calpain purified from human placenta.
    Clone
    28F3
    Isotype
    IgG1
  • Indications d'application
    ELISA: 0.5-1 μg/mL. Western blot: 0.5-1 μg/mL. Immunoprecipitation of both the native and denatured protein: 1-2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    20 mM Sodium Phosphate, pH 7.5, 150 mM Sodium Chloride, 50 % Glycerol and 3 mM Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    Date de péremption
    12 months
  • Antigène
    Calpain
    Abstract
    Calpain Produits
    Synonymes
    anticorps CG18152, anticorps CG7563, anticorps Dmel\\CG7563, anticorps EST C, anticorps calpain, anticorps Tb08.28A12.350, anticorps Calpain-A, anticorps hypothetical protein, anticorps calpain 11, anticorps calpain, anticorps CalpA, anticorps T11A5.6, anticorps CAPN11, anticorps Tb927.8.8330
    Sujet
    The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and -calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, u-calpain is active at micromolar (uM) concentrations of Ca++. In addition to the ubiquitously expressed m- and u-calpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.Synonyms: CANP-2, CANP1, CANPL1, CANPL2, CAPN1, CAPN2
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