KLRB1B anticorps

N° du produit ABIN264402

Détail du produit anti-KLRB1B anticorps

Antigène: KLRB1B (Killer Cell Lectin-Like Receptor Subfamily B Member 1B (KLRB1B))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)

Attributs du produit: Synonyms: NKRP1, Klrb1c NKR-P1

Purification: Purified

Immunogène: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized (BALB/c XC57BL/6)F1 (CbyB6F1) lymphokine-activated killer (LAK) cells and mouse myeloma cell line.

Clone: 1C10

Isotype: IgG

Information d'application

Indications d'application: Western Blot (1-5 μg/mL). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur KLRB1B

Antigène: KLRB1B (Killer Cell Lectin-Like Receptor Subfamily B Member 1B (KLRB1B))

Autre désignation: Natural Killer Cell Receptor-P1 (KLRB1B Produits)

Synonymes: anticorps Klrb1d, anticorps Ly55b, anticorps Ly55d, anticorps NKR-P1B, anticorps NKR-P1D, anticorps Nkrp1-b, anticorps Nkrp1d, anticorps Nkr-p1b, anticorps Nkrp1b, anticorps killer cell lectin-like receptor subfamily B member 1B, anticorps Klrb1b

Sujet: Natural Killer (NK) cells are large, granular lymphocytes found primarily in peripheral blood, where they make up about 10 % of the lymphocyte population. Their function is to defend against certain types of tumor cells and virally infected cells. When triggered, the cells release cytotoxic granules which induce either apoptosis or necrosis in the target cell. There are known to be two sets of cell surface receptor on NK cells which recognize target cells with opposing functions. One set, of which an example is NKR-P1 receptors, trigger cytokine release and cell cytotoxicity and the other set, of which Ly49A is an example, inhibit cytokine release. These receptors bind with MHC class I molecules on the surface of healthy cells which inhibits the release of cytokines. In virally infected or cancerous cells, class I MHC molecules are not expressed, inducing the release of cytokine. An activation signal is known to exist, however the mechanics of this signal are not very well understood.Synonyms: Klrb1c NKR-P1, NKRP1

UniProt: Q61970