SMC2 anticorps (AA 523-768)

N° du produit ABIN264446

L’anticorps anti-SMC2 Monoclonal Souris est utilisé pour la détection de SMC2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour SMC2 anticorps (AA 523-768) (ABIN264446)

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMC2 est non-conjugé

Application: Western Blotting (WB)

Clone: E1M

Détail du produit anti-SMC2 anticorps

Épitope: AA 523-768

Specificité: Recognizes SMC2/CAPE.

Attributs du produit: Synonyms: SMC protein 2, SMC-2, SMC2L1, CAP-E, Chromosome-associated protein E, XCAP-Ehomolog, Structural maintenance of chromosomes protein 2

Purification: Purified

Immunogène: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinantprotein corresponding to amino acids 523-768 of Human CAP-E and Mouse myeloma cells. Genename: SMC2

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1-5 μg/mL. Positive Control/Tissue Expression: HeLa cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur SMC2

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Autre désignation: SMC2 / CAPE

Sujet: CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.Synonyms: CAP-E, Chromosome-associated protein E, SMC protein 2, SMC-2, SMC2L1, Structural maintenance of chromosomes protein 2, XCAP-E homolog

ID gène: 10592

UniProt: O95347