Acetylated Lysine anticorps (acetylated)

N° du produit ABIN264880

Détail du produit anti-Acetylated Lysine anticorps

Antigène: Acetylated Lysine

Épitope: acetylated

Reactivité: Veuillez nous consulter SVP

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetylated Lysine est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity Chromatography

Immunogène: Acetylated KLH Conjugated

Isotype: IgG

Information d'application

Indications d'application: Western blot (6). Immunoprecipitation (7). ELISA. Immonoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Acetylated Lysine

Antigène: Acetylated Lysine

Abstract: Acetylated Lysine Produits

Synonymes: anticorps C-K-RAS, anticorps CFC2, anticorps K-RAS2A, anticorps K-RAS2B, anticorps K-RAS4A, anticorps K-RAS4B, anticorps KI-RAS, anticorps KRAS1, anticorps KRAS2, anticorps NS, anticorps NS3, anticorps RASK2, anticorps KRAS proto-oncogene, GTPase, anticorps KRAS

Classe de substances: Chemical

Sujet: Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common posttranscriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine N?-acetylation and deacetylation have been recognized as an emerging intracellular signaling mechanism that plays critical roles in regulating gene transcription, cell-cycle progression, apoptosis, DNA repair, and cytoskeletal organization (3). The regulation of protein acetylation status is impaired in the pathologies of cancer and polyglutamine diseases (4), and HDACs have become promising targets for anticancer drugs currently in development (5).Synonyms: AcK, acetyl Lysine, acetyl-Lysine