CCR5 anticorps (AA 6-20)
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- Antigène Voir toutes CCR5 Anticorps
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
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Épitope
- AA 6-20
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CCR5 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody reacts to CCR5 (6-20) (CD195).
- Purification
- Antigen Immunoaffiinity Chromatography
- Immunogène
- Synthetic peptide corresponding to amino acids 6 to 20 of Human CCR5.
- Isotype
- IgG
- Top Product
- Discover our top product CCR5 Anticorps primaire
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- Indications d'application
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Western Blot: 0.25 to 0.5 μg/mL. Detects an approximately 40 kDa band in THP-1 whole celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- Phosphate buffered saline solution containing 0.02 % Sodium Azide as a preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- DO NOT FREEZE!
- Stock
- 4 °C
- Stockage commentaire
- The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8 °C.
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- Antigène
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- Autre désignation
- CD195 / CCR5 (CCR5 Produits)
- Synonymes
- anticorps CC-CKR-5, anticorps CCCKR5, anticorps CCR-5, anticorps CD195, anticorps CKR-5, anticorps CKR5, anticorps CMKBR5, anticorps IDDM22, anticorps Ckr5, anticorps Cmkbr5, anticorps CCR1-L, anticorps GPCR, anticorps CCR5, anticorps AM4-7, anticorps C-C motif chemokine receptor 5 (gene/pseudogene), anticorps chemokine (C-C motif) receptor 5, anticorps C-C motif chemokine receptor 5, anticorps CCR5, anticorps Ccr5
- Sujet
- Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors1,2. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells3,4. CCR5 is required for the infection by HIV-1, HIV-2, and SIV1,2. The b-chemokines RANTES, MIP-1a and MIP-1b are the ligands for CCR5 and prevent infection by M-tropic HIV-13-5. CXC5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells6,7. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites8. CCR5 messenger RNA is expressed in lymphoid organs and monocytes.Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, CMKBR5, HIV-1 fusion coreceptor
- ID gène
- 1234
- NCBI Accession
- NP_000570
- UniProt
- P51681
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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