IRF7 anticorps (C-Term)
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- Antigène Voir toutes IRF7 Anticorps
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRF7 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody reacts to Interferon Regulatory Factor 7 (IRF7). Expressed predominantly in spleen, thymus and peripheral blood leukocytes, IRF7 is located in the nucleus and cytoplasm. The phosphorylated and active form accumulates selectivly in the nucleus.
- Purification
- Purified
- Immunogène
- Peptide corresponding to 14 amino acids near the carboxy-terminus of Human IRF7
- Isotype
- IgG
- Top Product
- Discover our top product IRF7 Anticorps primaire
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- Indications d'application
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Western Blot: 1-2 μg/mL. Positive control: Spleen, thymus and peripheral blood leukocytes.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline with 0.02 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- Antigène
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
- Autre désignation
- IRF7 (IRF7 Produits)
- Synonymes
- anticorps wu:fl24c03, anticorps zgc:66043, anticorps zgc:77947, anticorps IRF7, anticorps irf7, anticorps IRF-7H, anticorps IRF7A, anticorps IRF7B, anticorps IRF7C, anticorps IRF7H, anticorps interferon regulatory factor 7, anticorps irf7, anticorps IRF7, anticorps Irf7
- Sujet
- Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.Synonyms: IRF-7, Interferon regulatory factor 7
- ID gène
- 3665
- NCBI Accession
- NP_001563
- UniProt
- Q92985
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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