SULF2 anticorps
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- Antigène Voir toutes SULF2 Anticorps
- SULF2 (Sulfatase 2 (SULF2))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SULF2 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects Sulf2. Antibody tested on human brain lysate.
- Purification
- Purified
- Immunogène
- Synthetic peptide derived from the human Sulf2 protein
- Isotype
- IgG
- Top Product
- Discover our top product SULF2 Anticorps primaire
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- Indications d'application
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Western blot (0.05-0.1 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- Phosphate buffered saline with 0.08 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- Antigène
- SULF2 (Sulfatase 2 (SULF2))
- Autre désignation
- SULF2 (SULF2 Produits)
- Synonymes
- anticorps Sulf1, anticorps zgc:55612, anticorps SULF2, anticorps si:dkeyp-84g9.1, anticorps wu:fb48e04, anticorps HSULF-2, anticorps xtsulf2, anticorps 2010004N24Rik, anticorps AU020235, anticorps MSulf-2, anticorps mKIAA1247, anticorps sulfatase 2a, anticorps sulfatase 2, anticorps extracellular sulfatase Sulf-2, anticorps sulfatase 2b, anticorps sulfatase 2 S homeolog, anticorps sulf2a, anticorps SULF2, anticorps LOC100540921, anticorps sulf2, anticorps sulf2b, anticorps sulf2.S, anticorps Sulf2
- Sujet
- Sulf-2 exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Mammalian Sulfs are endoproteolytically processed and secreted into the extracellular space of transfected cells, where they exhibit both arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity against intact heparin. Though the molecular weight of full length human Sulf2 is 100455 Da (870 amino acids), the endogenous Sulf2 is found by western blot to be present at molecular weights of 24.4, 33.7 and 51-60 kDa. Higher molecular weight species may be found depending on tissue and/or cell type. Analysis of human tumor tissue and tumor cell lines suggests that HSulf-1 is misregulated in cancers. HSulf-1 is found in a variety of normal tissues but is down-regulated in tumor cell lines originating from ovarian, breast, pancreatic, renal, and hepatocellular carcinoma. Tumors formed by cells expressing Sulf demonstrate enhanced extracellular matrix deposition. The 6-O-sulfation of heparan sulfate of myeloma tumor cells may be a critical factor in determiningand regulating the in vivo growth of this cancer.Synonyms: Extracellular sulfatase Sulf-2, KIAA1247
- ID gène
- 55959
- NCBI Accession
- NP_001155313
- UniProt
- Q8IWU5
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