hCG anticorps

N° du produit ABIN265452

Détail du produit anti-hCG anticorps

Antigène: hCG (Chorionic Gonadotropin (hCG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp hCG est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of hCG β protein. (region surrounding Asp131)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur hCG

Antigène: hCG (Chorionic Gonadotropin (hCG))

Abstract: hCG Produits

Synonymes: anticorps CGB, anticorps AW108023, anticorps HCG, anticorps chorionic gonadotropin, beta polypeptide, anticorps ubiquitin-like 3, anticorps chorionic gonadotropin beta subunit 5, anticorps CGB, anticorps Ubl3, anticorps CGB5

Classe de substances: Hormone

Sujet: Choriogonadotropin is a hormone produced by the placenta in the first trimester of pregnancy and exists as a heterodimer formed from a unique β chain and an α chain common to all gonadotropins. The unique β chain confers biological specificity to choriogonadotropin, luteinizing hormone and follicle stimulating hormone. The secreted α subunit maps to human chromosome 6 and the β subunit of choriogonadotropin maps to human chromosome 19. Choriogonadotropin stimulates the ovaries to produce and maintain normal levels of the steroids essential for maintaining pregnancy, including estrogen and progesterone. Choriogonadotropin is a member of the cystine knot growth-factor superfamily, a group of proteins that contain a distinct arrangement of six cysteine residues and are expressed in placenta. The proper secretion and dimerization of choriogonadotropin depends on the conformation of the cystine knot, although biological activity is independent of this conformation.Synonyms: CGB, CGB3, Choriogonadotropin subunit beta, beta hCG, hCG-beta

Poids moléculaire: approx. 18 kDa

ID gène: 1082

NCBI Accession: NP_000728

UniProt: P01233