HDAC10 anticorps

N° du produit ABIN265454

Détail du produit anti-HDAC10 anticorps

Antigène: HDAC10 (Histone Deacetylase 10 (HDAC10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of HDAC10 protein. (region surrounding Glu24)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/5000-1/10000. Western blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HDAC10

Antigène: HDAC10 (Histone Deacetylase 10 (HDAC10))

Autre désignation: HDAC10 (HDAC10 Produits)

Synonymes: anticorps HDAC10, anticorps wu:fd19e10, anticorps zgc:55652, anticorps MGC115178, anticorps histone deacetylase 10, anticorps HD10, anticorps AW548891, anticorps Hd10, anticorps histone deacetylase 10, anticorps histone deacetylase 10 L homeolog, anticorps HDAC10, anticorps hdac10, anticorps hdac10.L, anticorps hda10, anticorps Hdac10

Sujet: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated mammalian RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.Synonyms: HD10, Histone deacetylase 10

Poids moléculaire: approx. 75 kDa

ID gène: 83933

NCBI Accession: NP_001152758

UniProt: Q969S8