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IL17 Receptor B anticorps (Alexa Fluor 647)
IL17RB
Reactivité: Souris
FACS
Hôte: Rat
Monoclonal
9B10
Alexa Fluor 647
N° du produit ABIN2657212
Détail du produit anti-IL17 Receptor B anticorps (Alexa Fluor 647)
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Antigène
Voir toutes IL17 Receptor B (IL17RB) Anticorps
IL17 Receptor B (IL17RB)
(Interleukin 17 Receptor B (IL17RB))
Reactivité
Toutes les réactivités sur IL17 Receptor B Anticorps
Souris
Hôte
Toutes les hôtes sur IL17 Receptor B Anticorps
Rat
Clonalité
Toutes les clonalités sur IL17 Receptor B Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers IL17 Receptor B Anticorps
Cet anticorp IL17 Receptor B est conjugé à/à la Alexa Fluor 647
Application
Tous les applications à travers IL17 Receptor B Anticorps.
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
9B10
Isotype
IgG2a kappa
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Protect from prolonged exposure to light. Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C
Détails sur IL17 Receptor B
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Antigène
IL17 Receptor B (IL17RB)
(Interleukin 17 Receptor B (IL17RB))
Autre désignation
IL-17RB (IL17RB Produits )
Synonymes
anticorps IL17RB, anticorps CRL4, anticorps EVI27, anticorps IL17BR, anticorps IL17RH1, anticorps Evi27, anticorps IL-17ER, anticorps IL-17Rh1, anticorps Il17br, anticorps interleukin 17 receptor B, anticorps IL17RB, anticorps Il17rb
Sujet
IL-17RB, also known as IL17RH1, belongs to the cytokine receptor family. IL-17RB possesses a unique intracellular signaling molecule called SEFIR, and is expressed similarily to fibroblast growth factor genes and IL-17R. It is reported to be expressed on iNKT cells, innate lymphoid cells (ILC), and Th2 cells. It binds IL-17B and IL-17E (IL-25) but not IL-17A or C. Its interaction with IL-25 has a higher affinity than that with IL-17B. Binding of IL-17RB and IL-25/IL-17E induces NF-kB mediated IL-8 production through interaction with TRAF6 and Act1. IL-17RB has been reported to play a role in autoimmune diseases such as rheumatoid arthritis and asthma.
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