Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

TRA-1-60(R) anticorps (Alexa Fluor 488)

Reactivité: Humain FACS, CyTOF Hôte: Souris Monoclonal TRA-1-60-R Alexa Fluor 488
N° du produit ABIN2657591
  • Antigène
    TRA-1-60(R)
    Reactivité
    Humain
    Hôte
    • 5
    Souris
    Clonalité
    • 5
    Monoclonal
    Conjugué
    • 2
    • 1
    • 1
    • 1
    Alexa Fluor 488
    Application
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
    Clone
    TRA-1-60-R
    Isotype
    IgM kappa
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from prolonged exposure to light. Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C
  • Antigène
    TRA-1-60(R)
    Autre désignation
    TRA-1-60-R
    Sujet
    TRA-1-60-R antibody recognizes the neuraminidase resistant form of TRA-1-60. TRA-1-60 is a 200-240 kD cell surface antigen expressed by human embryonic stem cells (ESC), embryonic germ cells (EG), and embryonal carcinoma cells. The expression of TRA-1-60 on human ESC is downregulated upon differentiation. The soluble form of TRA-1-60 has been found in the serum of patients with embryonic cancers. Historically, TRA-1-60 is a neuroaminidase-sensitive (TRA-1-60-S) carbohydrate epitope expressed on podocalyxin, a member of the mucin-like glycoprotein CD34 family. Podocalyxin is a type I transmembrane sialoprotein with anti-adhesion properties. Further studies have shown that some of TRA-1-60 is neuraminidase resistant (TRA-1-60-R). The two forms of TRA-1-60 are essentially indistinguishable in terms of their cellular reactivity except for the difference in neuraminidase sensitivity. Both of TRA-1-60-S and TRA-1-60-R appear to be the same molecular weight glycoproteins detected by Western blot.
Vous êtes ici:
Support technique