BST2 anticorps (Alexa Fluor 647)
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- Antigène Voir toutes BST2 Anticorps
- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BST2 est conjugé à/à la Alexa Fluor 647
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
- Purification
- The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
- Clone
- 927
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product BST2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C
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- Antigène
- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
- Autre désignation
- CD317 (BST2 Produits)
- Synonymes
- anticorps BST2, anticorps CD317, anticorps TETHERIN, anticorps 2310015I10Rik, anticorps Bst-2, anticorps C87040, anticorps DAMP-1, anticorps GREG, anticorps Damp1, anticorps bone marrow stromal cell antigen 2, anticorps bone marrow stromal antigen 2, anticorps BST2, anticorps LOC618737, anticorps Bst2
- Sujet
- CD317, known as BST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, or PDCA-1, is type II transmembrane glycoprotein with a molecular mass of 29-33 kD. It is predominantly expressed on Type I IFN-producing cells (IPCs) in naive mice, but is up-regulated on most cell types following stimulation with type I IFNs and IFN-gamma. It is highly expressed on terminally differentiated normal plasmacytoid dendritic cells and some tumor cells, such as multiple myeloma, renal cell carcinoma, and melanoma cells. BST2 is a recently identified, IFN-induced cellular response factor that blocks release of HIV-1 and other retroviruses from infected cells. BST2 has been found to be the natural ligand of ILT7 in human model.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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