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IL-21 anticorps (Alexa Fluor 647)
IL21
Reactivité: Humain
FACS
Hôte: Souris
Monoclonal
3A3-N2
Alexa Fluor 647
N° du produit ABIN2657954
Détail du produit anti-IL-21 anticorps (Alexa Fluor 647)
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Antigène
Voir toutes IL-21 (IL21) Anticorps
IL-21 (IL21)
(Interleukin 21 (IL21))
Reactivité
Toutes les réactivités sur IL-21 Anticorps
Humain
Hôte
Toutes les hôtes sur IL-21 Anticorps
Souris
Clonalité
Toutes les clonalités sur IL-21 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers IL-21 Anticorps
Cet anticorp IL-21 est conjugé à/à la Alexa Fluor 647
Application
Tous les applications à travers IL-21 Anticorps.
Flow Cytometry (FACS)
Réactivité croisée
Macaque rhésus
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
3A3-N2
Isotype
IgG1 kappa
Top Product
Discover our top product IL21 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Protect from prolonged exposure to light. Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C
Détails sur IL-21
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Antigène
IL-21 (IL21)
(Interleukin 21 (IL21))
Autre désignation
IL-21 (IL21 Produits )
Synonymes
anticorps IL-21, anticorps Za11, anticorps interleukin 21, anticorps IL21, anticorps Il21
Sujet
Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
Pathways
Signalistation JAK/STAT , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response
Vus récemment
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