The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
anticorps MGC179455, anticorps CLL-1, anticorps CLL1, anticorps DCAL-2, anticorps MICL, anticorps D230024O04, anticorps KLRL1, anticorps Micl, anticorps C-type lectin domain family 12 member A, anticorps C-type lectin domain family 12, member a, anticorps C-type lectin domain family 12, member A, anticorps CLEC12A, anticorps Clec12a
Sujet
CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family. Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases. Mouse CLEC12A is expressed on CD8 + dendritic cells (DCs), a proportion of CD8- dendritc cells, plasmacytoid DCs, monoctyes, macrophages, granulocytes, and B cells.