GP5 anticorps (APC)

N° du produit ABIN2658230

Détail du produit anti-GP5 anticorps (APC)

Antigène: GP5 (Glycoprotein V (Platelet) (GP5))

Reactivité: Souris, Rat

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp GP5 est conjugé à/à la APC

Application: Intracellular Flow Cytometry (ICFC)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: 1C2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur GP5

Antigène: GP5 (Glycoprotein V (Platelet) (GP5))

Autre désignation: CD42d (GP5 Produits)

Synonymes: anticorps lib, anticorps GPV, anticorps PLGPV, anticorps CD42d, anticorps glycoprotein V platelet L homeolog, anticorps glycoprotein V platelet, anticorps glycoprotein 5 (platelet), anticorps glycoprotein V (platelet), anticorps gp5.L, anticorps GP5, anticorps Gp5

Sujet: CD42d is an 83 kD surface glycoprotein that non-covalently associates with GPIb and GPIX to form a receptor complex for von Willebrand factor on megakaryocytes and resting platelets. Binding sites for von Willebrand factor and thrombin have been localized to the GPIba chain of the GPI-b-V-IX complex. Platelet activation with thrombin cleaves the GPI-b-V-IX complex to release a 69 kD soluble fragment. Presence of the GPI-b-V-IX complex is important in Bernard-Soulier syndrome, a rare bleeding disorder.