NGFR anticorps (APC)
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- Antigène Voir toutes NGFR Anticorps
- NGFR (Nerve Growth Factor Receptor (NGFR))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NGFR est conjugé à/à la APC
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Application
- Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
- Réactivité croisée
- Singe, Raccoon (Procyon lotor), Mouton, Chat, Chien, Porc, Lapin
- Purification
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
- Clone
- ME20-4
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product NGFR Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- NGFR (Nerve Growth Factor Receptor (NGFR))
- Autre désignation
- CD271 (NGFR Produits)
- Synonymes
- anticorps ngfr, anticorps wu:fb38c02, anticorps wu:fc10h01, anticorps CD271, anticorps Gp80-LNGFR, anticorps TNFRSF16, anticorps p75(NTR), anticorps p75NTR, anticorps LNGFR, anticorps RNNGFRR, anticorps Tnfrsf16, anticorps p75, anticorps NRH1b, anticorps fullback, anticorps nrh1, anticorps p75ntr, anticorps tnfrsf16, anticorps p75NGFR, anticorps nerve growth factor receptor, anticorps neurotrophin receptor associated death domain, anticorps nerve growth factor receptor S homeolog, anticorps nerve growth factor receptor (TNFR superfamily, member 16), anticorps NGFR, anticorps nradd, anticorps Ngfr, anticorps ngfr.S
- Sujet
- CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.
- Pathways
- Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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