CD28 anticorps (PerCP-Cy5.5)
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- Antigène Voir toutes CD28 Anticorps
- CD28
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD28 est conjugé à/à la PerCP-Cy5.5
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Application
- Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
- Réactivité croisée
- Chimpanzé, Babouin, Cynomolgus, Macaque rhésus, Pigtailed Macaque, Capuchin Monkey, Sooty mangabey (Cercocebus atys), Squirrel Monkey (Saimiri spec.)
- Purification
- The antibody was purified by affinity chromatography, and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
- Clone
- CD28-2
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD28 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- CD28
- Autre désignation
- CD28 (CD28 Produits)
- Synonymes
- anticorps Tp44, anticorps CD28RNA, anticorps cd28, anticorps CD28 molecule, anticorps CD28 antigen, anticorps Cd28 molecule, anticorps CD28 molecule L homeolog, anticorps CD28, anticorps Cd28, anticorps cd28.L
- Sujet
- CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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