Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CCL28 anticorps (Biotin)

CCL28 Reactivité: Souris FACS, CyTOF Hôte: Chèvre Polyclonal Poly5242 Biotin
N° du produit ABIN2660745
  • Antigène Voir toutes CCL28 Anticorps
    CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))
    Reactivité
    • 22
    • 6
    • 2
    Souris
    Hôte
    • 20
    • 4
    • 1
    Chèvre
    Clonalité
    • 21
    • 4
    Polyclonal
    Conjugué
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CCL28 est conjugé à/à la Biotin
    Application
    • 17
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
    Purification
    The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Clone
    Poly5242
    Isotype
    IgG
    Top Product
    Discover our top product CCL28 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from prolonged exposure to light. Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))
    Autre désignation
    CCL28 (CCL28 Produits)
    Synonymes
    anticorps Scya28, anticorps CCL28, anticorps ccl28, anticorps nrpb, anticorps enc-1, anticorps pig10, anticorps Encr-3, anticorps klhl35, anticorps Xencr-3, anticorps tp53i10, anticorps LOC100303767, anticorps CCK1, anticorps MEC, anticorps SCYA28, anticorps C-C motif chemokine ligand 28, anticorps ectodermal-neural cortex 1 (with BTB domain), anticorps C-C motif chemokine 28, anticorps chemokine (C-C motif) ligand 28, anticorps Ccl28, anticorps CCL28, anticorps ccl28, anticorps enc1, anticorps LOC100303767
    Sujet
    Mouse CCL28 was identified in an EST database using a human chemokine consensus sequence. CCL28 is constitutively expressed by mucosal epithelial cells such as exocrine glands, trachea, and colon. Acinar epithelial cells in human and mouse salivary glands are strongly positive for CCL28 by immunostaining, and human saliva and milk contain high concentrations of CCL28. Furthermore, it is known that human and mouse CCL28 have antimicrobial activity attributed to the C-terminus of CCL28 against Candida albicans, Gram-negative bacteria, and Gram-positive bacteria. In addition, using a CCR10 deficient mouse model, it was shown that CCR10 plays a critical role in localization and accumulation of IgA ASC in lactating mammary glands. Also, it has been described that CCL28 is upregulated in epithelial inflammation and this upregulation allows the recruitment of Tregs expressing CCR10. In fact, a subpopulation of CCR10-expressing CD25+ CD4+ Foxp3+ Tregs with potent anti-inflammatory properties was isolated from a chronically inflamed human liver. Information suggests that tumor hypoxia promotes the recruitment of Treg cells through induction of expression of CCL28, and this induction is mediated by the hypoxia inducible factor-1α (HIF-1α). Therefore, tumor hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells.
Vous êtes ici:
Support technique