Cet anticorps anti-CXCR5 Monoclonal Rat conjugué à Biotin (Clone L138D7) (ABIN2660750) détecte spécifiquement CXCR5 dans FACS.
L’anticorps est réactif avec des échantillons de Souris.
CD185 is also known as CXCR5. It is the receptor for chemokine CXCL13/BLC, which is chemotactic for B cells. CXCR5 is expressed on B cells and a subset of T cells in the spleen, neuronal tissue, lymph nodes, and bone marrow. It is important for migration of B cells into the B cell follicles of the spleen and Peyer's patches. Follicular helper T cells (Tfh) also express CXCR5 and the ability of these cells to migrate to the lymph node is modulated by the balanced expression of CCR7 and CXCR5.