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TNFRSF1B anticorps (Biotin)
TNFRSF1B
Reactivité: Souris
ELISA, IHC, FACS, Func
Hôte: Hamster
Monoclonal
TR75-32-4
Biotin
N° du produit ABIN2660925
Détail du produit anti-TNFRSF1B anticorps (Biotin)
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Antigène
Voir toutes TNFRSF1B Anticorps
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
Reactivité
Toutes les réactivités sur TNFRSF1B Anticorps
Souris
Hôte
Toutes les hôtes sur TNFRSF1B Anticorps
Hamster
Clonalité
Toutes les clonalités sur TNFRSF1B Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers TNFRSF1B Anticorps
Cet anticorp TNFRSF1B est conjugé à/à la Biotin
Application
Tous les applications à travers TNFRSF1B Anticorps.
ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Functional Studies (Func)
Purification
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone
TR75-32-4
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur TNFRSF1B
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Antigène
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
Autre désignation
CD120b (TNFRSF1B Produits )
Synonymes
anticorps CD120b, anticorps TBPII, anticorps TNF-R-II, anticorps TNF-R75, anticorps TNFBR, anticorps TNFR1B, anticorps TNFR2, anticorps TNFR80, anticorps p75, anticorps p75TNFR, anticorps TNF-RII/TNFRSF1B, anticorps TNFR-II, anticorps TNFRSF1B, anticorps TNF-R2, anticorps TNF-alphaR2, anticorps TNFRII, anticorps TNFalpha-R2, anticorps Tnfr-1, anticorps Tnfr2, anticorps rank, anticorps zgc:163064, anticorps TNF receptor superfamily member 1B, anticorps tumor necrosis factor receptor superfamily, member 1b, anticorps tumor necrosis factor receptor superfamily, member 1B, anticorps TNFRSF1B, anticorps Tnfrsf1b, anticorps tnfrsf1b
Sujet
CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels, the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state. The TR75-32.4 antibody has been shown to block ligand-induced receptor signaling.
Pathways
Signalisation NF-kappaB , Apoptose , Cellular Response to Molecule of Bacterial Origin , Hepatitis C , Ubiquitin Proteasome Pathway
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