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LAG3 anticorps (Biotin)

LAG3 Reactivité: Souris IHC, FACS, IF Hôte: Rat Monoclonal C9B7W Biotin
N° du produit ABIN2660995
  • Antigène Voir toutes LAG3 Anticorps
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Reactivité
    • 87
    • 37
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 52
    • 34
    • 11
    • 4
    Rat
    Clonalité
    • 53
    • 45
    • 1
    Monoclonal
    Conjugué
    • 53
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LAG3 est conjugé à/à la Biotin
    Application
    • 68
    • 36
    • 32
    • 29
    • 25
    • 21
    • 15
    • 13
    • 13
    • 10
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Clone
    C9B7W
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product LAG3 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Autre désignation
    CD223 (LAG3 Produits)
    Synonymes
    anticorps CD223, anticorps LAG-3, anticorps Ly66, anticorps lymphocyte activating 3, anticorps lymphocyte-activation gene 3, anticorps LAG3, anticorps Lag3
    Sujet
    CD223, also known as LAG-3, is 70 kD type I transmembrane glycoprotein within the Ig superfamily. It is the gene product of lymphocyte activation gene-3 (Lag3) with structural similarity to CD4. CD223 is expressed on activated T cells and NK cells, as well as T regulatory cells. CD223, like CD4, binds MHC class II molecules, but with higher affinity than CD4. In association with the CD3 complex, CD223 has been shown as a negative regulatory molecule to inhibit TCR-mediated signaling and regulate homeostatic T cell expansion. In contrast to inhibition, CD223 has an activation function to promote immune responses by inducing MHC class II signaling in antigen presenting cells.
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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