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CD8 alpha anticorps (FITC)
CD8A
Reactivité: Humain
ICFC
Hôte: Souris
Monoclonal
HIT8a
FITC
N° du produit ABIN2661843
Détail du produit anti-CD8 alpha anticorps (FITC)
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Antigène
Voir toutes CD8 alpha (CD8A) Anticorps
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Reactivité
Toutes les réactivités sur CD8 alpha Anticorps
Humain
Hôte
Toutes les hôtes sur CD8 alpha Anticorps
Souris
Clonalité
Toutes les clonalités sur CD8 alpha Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CD8 alpha Anticorps
Cet anticorp CD8 alpha est conjugé à/à la FITC
Application
Tous les applications à travers CD8 alpha Anticorps.
Intracellular Flow Cytometry (ICFC)
Réactivité croisée
Chimpanzé, Marmoset
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
HIT8a
Isotype
IgG1 kappa
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Protect from prolonged exposure to light. Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur CD8 alpha
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Antigène
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Autre désignation
CD8a (CD8A Produits )
Synonymes
anticorps cd8, anticorps LOC100136450, anticorps BB154331, anticorps Ly-2, anticorps Ly-35, anticorps Ly-B, anticorps Lyt-2, anticorps zgc:136643, anticorps CD8, anticorps Leu2, anticorps MAL, anticorps p32, anticorps RHACD8-4, anticorps CD8a molecule, anticorps uncharacterized LOC100125537, anticorps CD8 alpha, anticorps CD8 antigen, alpha chain, anticorps T-cell surface glycoprotein CD8 alpha chain, anticorps Cd8a, anticorps LOC100125537, anticorps LOC100136450, anticorps CD8A, anticorps cd8a, anticorps LOC100126556
Sujet
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Pathways
TCR Signaling
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