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MHC Class II I-Ek anticorps (FITC)

Reactivité: Souris FACS, ICFC Hôte: Souris Monoclonal 14-4-4S FITC
N° du produit ABIN2661929
  • Antigène Tous les produits MHC Class II I-Ek
    MHC Class II I-Ek
    Reactivité
    • 12
    • 1
    Souris
    Hôte
    • 12
    Souris
    Clonalité
    • 12
    Monoclonal
    Conjugué
    • 5
    • 2
    • 2
    • 2
    • 1
    Cet anticorp MHC Class II I-Ek est conjugé à/à la FITC
    Application
    • 11
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
    Réactivité croisée (Details)
    Cross-reacts with H-2d,p,r haplotypes. Mice of the H-2b,f,q,s haplotypes do not express I-E antigens. Cross-reacts with rat MHC class II antigen RT1D
    Attributs du produit
    The 14-4-4S antibody reacts with the I-Ek MHC class II alloantigen. These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2k bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins. The 14-4-4S antibody cross-reacts with cells from mice of the H-2d, H-2p, and H-2r haplotypes and the rat MHC class II antigen RT1D. Cells from mice of the H-2b, H-2f, H-2q, and H-2s haplotypes do not express I-E antigen. The 14-4-4S antibody has been reported to block antigen presentation and induce differentiation of mouse cells bearing I-Ek.
    Purification
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Clone
    14-4-4S
    Isotype
    IgG2a kappa
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from prolonged exposure to light. Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    MHC Class II I-Ek
    Autre désignation
    I-Ek/rat RT1D (MHC Class II I-Ek Produits)
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