GPR56 anticorps (PE)

N° du produit ABIN2662735

Détail du produit anti-GPR56 anticorps (PE)

Antigène: GPR56 (G Protein-Coupled Receptor 56 (GPR56))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GPR56 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: CG4

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur GPR56

Antigène: GPR56 (G Protein-Coupled Receptor 56 (GPR56))

Autre désignation: GPR56 (GPR56 Produits)

Synonymes: anticorps fc49b10, anticorps wu:fc49b10, anticorps BFPP, anticorps TM7LN4, anticorps TM7XN1, anticorps Cyt28, anticorps GPR56, anticorps adhesion G protein-coupled receptor G1, anticorps G protein-coupled receptor 56, anticorps ADGRG1, anticorps adgrg1, anticorps Adgrg1, anticorps GPR56

Sujet: GPR56, also known as TM7XN1, is an orphan G-protein-coupled receptor (GPCR) containing seven transmembrane domains and a mucin-like domain in the N-terminal region. The total length of the human GPR56 gene is approximately 15 kb, and it consists of 13 exons and encodes 693 amino acids. GPR56 is expressed in a wide range of tissues, such as brain, thyroid gland, and heart. Mutations in human GPR56 gene were found to cause a specific brain malformation called bilateral frontoparietal polymicrogyria. Recently, GPR56 was found specifically expressed on cytotoxic NK and T lymphocytes, including CD8+, CD4+, and γδ T cells, which might affect the migratory properties of these cells. GPR56 was also found significantly downregulated in some cancer cells, suggesting that it may play a role in growth suppression and cancer metastasis.