Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
Purification
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
HLA-DM is a non-classical MHC molecule, comprised of one α chain and one β chain, which is expressed by antigen presenting cells. HLA-DM acts as a chaperon that stabilizes the MHC class II molecule in the lyzosome, while enhances the exchange of CLIP for the antigenic peptide.