CD51 anticorps (PE)
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- Antigène Voir toutes CD51 (ITGAV) Anticorps
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD51 est conjugé à/à la PE
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- Clone
- RMV-7
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ITGAV Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Autre désignation
- CD51 (ITGAV Produits)
- Synonymes
- anticorps 1110004F14Rik, anticorps 2610028E01Rik, anticorps CD51, anticorps D430040G12Rik, anticorps MSK8, anticorps VNRA, anticorps VTNR, anticorps Cd51, anticorps integrin subunit alpha V, anticorps integrin alpha V, anticorps ITGAV, anticorps Itgav
- Sujet
- CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β 1, β3, β5 or β6, these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αv integrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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