C3a anticorps
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- Antigène Voir toutes C3a Anticorps
- C3a (Complement Fragment 3a (C3a))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp C3a est non-conjugé
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Application
- Immunoprecipitation (IP), ELISA, Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- K13-16
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product C3a Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- C3a (Complement Fragment 3a (C3a))
- Autre désignation
- C3a/C3a/C3 (C3a Produits)
- Synonymes
- anticorps AHUS5, anticorps ARMD9, anticorps ASP, anticorps C3a, anticorps C3b, anticorps CPAMD1, anticorps AI255234, anticorps HSE-MSF, anticorps Plp, anticorps C3d, anticorps complement C3, anticorps complement component 3, anticorps C3
- Sujet
- C3, complement component 3, is a 195 kD glycoprotein heterodimer that is linked by disulfide bonds. It is the fourth complement component to react in the classical pathway and it is also a reactant in the alternative complement pathway. C3 convertase splits C3 into C3b and C3a. C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Macrophages and neutrophils have receptors for C3b. C3a is released into the surrounding fluids. It can bind to receptors on basophils and mast cells triggering them to release their vasoactive contents (e.g., histamine). Because of the role of these materials in anaphylaxis, C3a is called an anaphylatoxin. In blood, the C3a fragment is rapidly desarginated by serum carboxypeptidase N enzyme to generate C3a desArg. Both C3a and C3a desArg are not glycosylated.
- Pathways
- Système du Complément
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