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CCRL1 anticorps
CCRL1
Reactivité: Humain
ELISA, IHC, ICFC
Hôte: Souris
Monoclonal
13E11
unconjugated
N° du produit ABIN2664103
Détail du produit anti-CCRL1 anticorps
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Antigène
Voir toutes CCRL1 Anticorps
CCRL1
(Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
Reactivité
Toutes les réactivités sur CCRL1 Anticorps
Humain
Hôte
Toutes les hôtes sur CCRL1 Anticorps
Souris
Clonalité
Toutes les clonalités sur CCRL1 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CCRL1 Anticorps
Cet anticorp CCRL1 est non-conjugé
Application
Tous les applications à travers CCRL1 Anticorps.
ELISA, Immunohistochemistry (IHC), Intracellular Flow Cytometry (ICFC)
Purification
The antibody was purified by affinity chromatography.
Clone
13E11
Isotype
IgG2b kappa
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur CCRL1
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Antigène
CCRL1
(Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
Autre désignation
CCX-CKR (CCRL1 Produits )
Synonymes
anticorps CC-CKR-11, anticorps CCBP2, anticorps CCR-11, anticorps CCR10, anticorps CCR11, anticorps CCRL1, anticorps CCX CKR, anticorps CCX-CKR, anticorps CKR-11, anticorps PPR1, anticorps VSHK1, anticorps A630091E18Rik, anticorps CCX-CKR1, anticorps Ccrl1, anticorps Cmkbrl1, anticorps atypical chemokine receptor 4, anticorps chemokine (C-C motif) receptor-like 1, anticorps Chemokine receptor-like 1, anticorps chemerin chemokine-like receptor 1, anticorps ACKR4, anticorps Ackr4, anticorps CCRL1, anticorps cml1, anticorps CMKLR1
Sujet
Human CCX-CKR, also known as CCRL1, is a 40 kD, G-protein-coupled, seven transmembrane receptor. CCRL1 is a decoy receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25 that regulates chemotaxis of lymphocytes and cancer cells. Chemokine binding by CCX-CKR causes its internalization, reducing levels of available chemokine, and thus regulating migration of lymphocytes and cancerous cells. CCX-CKR is expressed by stromal cells of skin-draining lymph nodes, thymic epithelial cells, and immature dendritic cells (DCs). A low CCX-CKR expression in tumor cells correlates with a poor survival rate of breast cancer patients.
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