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CSF1R anticorps
CSF1R
Reactivité: Humain
FACS
Hôte: Rat
Monoclonal
9-4D2-1E4
unconjugated
N° du produit ABIN2664136
Détail du produit anti-CSF1R anticorps
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Antigène
Voir toutes CSF1R Anticorps
CSF1R
(Colony Stimulating Factor 1 Receptor (CSF1R))
Reactivité
Toutes les réactivités sur CSF1R Anticorps
Humain
Hôte
Toutes les hôtes sur CSF1R Anticorps
Rat
Clonalité
Toutes les clonalités sur CSF1R Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CSF1R Anticorps
Cet anticorp CSF1R est non-conjugé
Application
Tous les applications à travers CSF1R Anticorps.
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
9-4D2-1E4
Isotype
IgG1 kappa
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur CSF1R
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Antigène
CSF1R
(Colony Stimulating Factor 1 Receptor (CSF1R))
Autre désignation
CD115 (CSF1R Produits )
Synonymes
anticorps AI323359, anticorps CD115, anticorps CSF-1R, anticorps Csfmr, anticorps Fim-2, anticorps Fms, anticorps M-CSF-R, anticorps M-CSFR, anticorps C-FMS, anticorps CSFR, anticorps FIM2, anticorps FMS, anticorps HDLS, anticorps PDGFRB, anticorps MGC89146, anticorps CSF-1-R, anticorps c-fms, anticorps mrfms, anticorps CSF1, anticorps M-CSF, anticorps csf1r, anticorps fms, anticorps panther, anticorps colony stimulating factor 1 receptor, anticorps macrophage colony-stimulating factor receptor, anticorps colony stimulating factor 1 receptor, a, anticorps Csf1r, anticorps CSF1R, anticorps m-csfr, anticorps csf1r, anticorps csf1ra
Sujet
CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitinylation of intracellular residues. The natural ligands of CD115 include M-CSF and IL-34. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, plasmacytoid and conventional dendritic cells, and osteoclasts.
Pathways
Signalisation RTK , Inositol Metabolic Process , Cell-Cell Junction Organization
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