Integrin beta 2 anticorps
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- Antigène Voir toutes Integrin beta 2 (ITGB2) Anticorps
- Integrin beta 2 (ITGB2)
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Integrin beta 2 est non-conjugé
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Application
- Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- M18-2
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product ITGB2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- Integrin beta 2 (ITGB2)
- Autre désignation
- CD18 (ITGB2 Produits)
- Synonymes
- anticorps CD18, anticorps LAD, anticorps LCAMB, anticorps LFA-1, anticorps MAC-1, anticorps MF17, anticorps MFI7, anticorps 2E6, anticorps AI528527, anticorps Cd18, anticorps Lfa1, anticorps ITGB2, anticorps itgb2, anticorps itgb2-a, anticorps itgb2-b, anticorps integrin subunit beta 2, anticorps integrin beta 2, anticorps integrin subunit beta 2 S homeolog, anticorps ITGB2, anticorps Itgb2, anticorps itgb2.S
- Sujet
- CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.
- Pathways
- Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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