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RANKL anticorps
TNFSF11
Reactivité: Humain
IHC, FACS
Hôte: Souris
Monoclonal
MIH24
unconjugated
N° du produit ABIN2664446
Détail du produit anti-RANKL anticorps
(cache)
Antigène
Voir toutes RANKL (TNFSF11) Anticorps
RANKL (TNFSF11)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
Reactivité
Toutes les réactivités sur RANKL Anticorps
Humain
Hôte
Toutes les hôtes sur RANKL Anticorps
Souris
Clonalité
Toutes les clonalités sur RANKL Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers RANKL Anticorps
Cet anticorp RANKL est non-conjugé
Application
Tous les applications à travers RANKL Anticorps.
Immunohistochemistry (IHC), Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
MIH24
Isotype
IgG2b kappa
Top Product
Discover our top product TNFSF11 Anticorps primaire
Alternatives
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 210-317) antibody
TNFSF11
Reactivité: Humain, Souris, Rat, Lapin
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
(cache)
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
(cache)
Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur RANKL
(cache)
Antigène
RANKL (TNFSF11)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
Autre désignation
CD254 (TNFSF11 Produits )
Synonymes
anticorps CD254, anticorps ODF, anticorps OPGL, anticorps OPTB2, anticorps RANKL, anticorps TRANCE, anticorps hRANKL2, anticorps sOdf, anticorps TNFSF11, anticorps Ly109l, anticorps OPG, anticorps Trance, anticorps cd254, anticorps odf, anticorps opgl, anticorps optb2, anticorps rankl, anticorps sodf, anticorps tnfsf11, anticorps trance, anticorps TNF superfamily member 11, anticorps tumor necrosis factor (ligand) superfamily, member 11, anticorps TNF receptor superfamily member 11b, anticorps TNF superfamily member 11 L homeolog, anticorps TNFSF11, anticorps Tnfsf11, anticorps TNFRSF11B, anticorps tnfsf11.L
Sujet
Human CD254, also known as RANKL, TRANCE, and OPGL, is a type II transmembrane protein in the TNF superfamily that has two forms: a membrane-anchored protein and a secreted protein. Its extracellular domain is related to TRAIL, FasL, and TNF. CD254 is expressed on osteoclasts and activated T cells. It has been implicated in the regulation of the interactions between T cells and dendritic cells. It plays an important role in osteoclast differentiation and bone resorption. CD254 activates JNK and NF-κB and induces the expression of IL-1, IL-6, IL-12, and IL-15 in dendritic cells.
Pathways
Signalisation NF-kappaB
Vus récemment
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