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- Antigène Voir toutes CD40 Anticorps
- CD40
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD40 est non-conjugé
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Application
- Flow Cytometry (FACS)
- Réactivité croisée
- Babouin, Chimpanzé, Cynomolgus, Macaque rhésus, Squirrel Monkey (Saimiri spec.)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- 5C3
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD40 Anticorps primaire
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anti-CD40 (CD40) (AA 26-187) antibody
CD40 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-CD40 (CD40) antibodyCD40 Reactivité: Humain FACS, IHC, IF, StM, DNA Mic Hôte: Souris Monoclonal C40-1605 unconjugated
anti-CD40 (CD40) (AA 21-193) antibodyCD40 Reactivité: Humain FACS, WB, ELISA, IHC, ICC, Neut Hôte: Souris Monoclonal 4E1B9 unconjugated
anti-CD40 (CD40) (AA 29-107) antibodyCD40 Reactivité: Humain FACS, ELISA, IHC, StM, Coat Hôte: Souris Monoclonal C40-2383 unconjugated
anti-CD40 (CD40) (C-Term) antibodyCD40 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-CD40 (CD40) (AA 71-187) antibodyCD40 Reactivité: Humain WB, IF Hôte: Souris Monoclonal 41-CD40 unconjugated
anti-CD40 (CD40) (AA 1-360) antibodyCD40 Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-CD40 (CD40) (Extracellular Domain) antibodyCD40 Reactivité: Humain FACS, IHC, St Hôte: Souris Monoclonal 5C3 unconjugated
anti-CD40 (CD40) antibody (FITC)CD40 Reactivité: Humain FACS Hôte: Souris Monoclonal HI40a FITC
anti-CD40 (CD40) antibodyCD40 Reactivité: Humain FACS, IHC, IP, Act Hôte: Lapin Chimeric G28-5 unconjugated Recombinant Antibody
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- CD40
- Autre désignation
- CD40 (CD40 Produits)
- Synonymes
- anticorps Bp50, anticorps CDW40, anticorps TNFRSF5, anticorps p50, anticorps AI326936, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps TNFSF5, anticorps CD40 molecule, anticorps CD40 antigen, anticorps CD40, anticorps Cd40
- Sujet
- CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
- Pathways
- Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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