PAX9 anticorps

N° du produit ABIN2665320

Détail du produit anti-PAX9 anticorps

Antigène: PAX9 (Paired Box 9 (PAX9))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX9 est non-conjugé

Application: Multiplex Assay (MA)

Purification: The antibody was purified by affinity chromatography.

Clone: 14D10A24

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur PAX9

Antigène: PAX9 (Paired Box 9 (PAX9))

Autre désignation: PAX9 (PAX9 Produits)

Synonymes: anticorps STHAG3, anticorps ChPax9, anticorps PAX-9, anticorps Pax-9, anticorps xpax9, anticorps xpax-9, anticorps paired box 9, anticorps paired box 9 L homeolog, anticorps PAX9, anticorps pax9, anticorps Pax9, anticorps pax9.L

Sujet: PAX9 is a transcription factor belonging to the PAX family, which is composed of nine members defined by the presence of a paired box domain responsible for DNA binding. PAX9 is expressed at the E10 stage and downregulated at the bell stage. It is controlled by Fgf/Bmp signaling and plays an essential role in tooth development. PAX9 deficient mice fail to form teeth and show developmental arrest at the bud stage. In humans, heterozygous mutation in PAX9 is associate with tooth agenesis. These findings support the role of PAX9 in tooth development.