IL-22 anticorps (AA 34-179)
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- Antigène Voir toutes IL-22 (IL22) Anticorps
- IL-22 (IL22) (Interleukin 22 (IL22))
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Épitope
- AA 34-179
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Reactivité
- Souris
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-22 est non-conjugé
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Application
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography.
- Immunogène
- AA 34-179 (Accession# NM_016971), was expressed in E. Coli
- Clone
- Poly5164
- Isotype
- Ig Fraction, IgG
- Top Product
- Discover our top product IL22 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2 and 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- IL-22 (IL22) (Interleukin 22 (IL22))
- Autre désignation
- IL-22 (IL22 Produits)
- Synonymes
- anticorps IL-21, anticorps IL-22, anticorps IL-D110, anticorps IL-TIF, anticorps ILTIF, anticorps TIFIL-23, anticorps TIFa, anticorps zcyto18, anticorps IL-22a, anticorps ILTIFa, anticorps Iltif, anticorps RGD1561292, anticorps interleukin-22, anticorps interleukin 22, anticorps IL22, anticorps il22, anticorps Il22
- Sujet
- IL-22 is a cytokine structurally related to IL-10. Mouse IL-22 consists of 179 amino acids and has a predicted molecular weight of 20 kD. It is secreted primarily by Th17, Th1, Th2, lymphoid tissue inducer cells (LTi), and subsets of natural killer cells. It has been reported that aryl hydrocarbon receptor (AhR) expression is essential for the production of IL-22 by TCRγδ T cells. AhR activation increases Th17 polarization and induces IL-22 production. IL-22 functions by engaging the heterodimeric IL-22 receptor (IL-22R) complex, consisting of two receptor subunits, IL-22R1 and IL-10Rβ. IL-22 acts on nonhematopoietic tissue cells, such as epithelial cells of the digestive and respiratory systems and keratinocytes of the skin. IL-22 is involved in inflammatory processes such as dermal inflammation, psoriasis, inflammatory bowel disease, hepatitis, and Crohn's disease. Moreover, it plays a critical role in mucosal immunity and the wound healing process.
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