BCL11B anticorps
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- Antigène Voir toutes BCL11B Anticorps
- BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
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Reactivité
- Humain
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BCL11B est non-conjugé
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Application
- Flow Cytometry (FACS)
- Réactivité croisée
- Souris, Poisson Zèbre
- Réactivité croisée (Details)
- Mouse, Zebrafish
- Purification
- Protein G affinity purified.
- Clone
- 25B6
- Isotype
- IgG
- Top Product
- Discover our top product BCL11B Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Hepes-buffered solution, pH 7.5, 0.02 % Sodium azide .
- Stock
- 4 °C
- Stockage commentaire
- Upon receipt, store undiluted between 2°C and 8°C.
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- Antigène
- BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
- Autre désignation
- Bcl11b (BCL11B Produits)
- Synonymes
- anticorps BCL11B, anticorps 9130430L19Rik, anticorps AI604821, anticorps B630002E05Rik, anticorps BCL-11B, anticorps Ctip2, anticorps Rit1, anticorps ATL1, anticorps ATL1-alpha, anticorps ATL1-beta, anticorps ATL1-delta, anticorps ATL1-gamma, anticorps CTIP-2, anticorps CTIP2, anticorps RIT1, anticorps ZNF856B, anticorps hRIT1-alpha, anticorps B-cell CLL/lymphoma 11B, anticorps B cell leukemia/lymphoma 11B, anticorps B-cell CLL/lymphoma 11B (zinc finger protein), anticorps BCL11B, anticorps Bcl11b
- Sujet
- The transcription factor Bcl11b is expressed in thymus, mainly T cells. It is indispensable for T lineage development. When Bcl11b was deleted, T cells from all developmental stages acquired NK cell properties and concomitantly lost or decreased T cell-associated gene expression. These induced T-to-natural killer (ITNK) cells, which were morphologically and genetically similar to conventional NK cells, killed tumor cells in vitro, and effectively prevented tumor metastasis in vivo. Therefore, ITNKs may represent a new cell source for cell-based therapies.
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