Retinoblastoma Binding Protein 8 anticorps (AA 620-897)
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- Antigène Voir toutes Retinoblastoma Binding Protein 8 (RBBP8) Anticorps
- Retinoblastoma Binding Protein 8 (RBBP8)
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Épitope
- AA 620-897
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Retinoblastoma Binding Protein 8 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Purification
- Protein A Chromatography
- Immunogène
- This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.
- Clone
- 14-1
- Isotype
- IgG1
- Top Product
- Discover our top product RBBP8 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Stock
- -20 °C
- Stockage commentaire
- Antibodies in solution can be stored at -20 °C for 2 years.
- Date de péremption
- 6 months
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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." dans: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." dans: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).
: "Quantitation of DNA double-strand break resection intermediates in human cells." dans: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).
: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." dans: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).
: "An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway." dans: Nature structural & molecular biology, Vol. 18, Issue 1, pp. 80-4, (2011) (PubMed).
: "BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP." dans: Genes & development, Vol. 20, Issue 13, pp. 1721-6, (2006) (PubMed).
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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." dans: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
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- Antigène
- Retinoblastoma Binding Protein 8 (RBBP8)
- Autre désignation
- CtIP (RBBP8 Produits)
- Synonymes
- anticorps COM1, anticorps CTIP, anticorps JWDS, anticorps RIM, anticorps SAE2, anticorps SCKL2, anticorps 9930104E21Rik, anticorps CtIP, anticorps RBBP-8, anticorps RGD1308872, anticorps RBBP8, anticorps DKFZp469K0714, anticorps RB binding protein 8, endonuclease, anticorps retinoblastoma binding protein 8, endonuclease, anticorps retinoblastoma binding protein 8 L homeolog, anticorps retinoblastoma binding protein 8, anticorps RBBP8, anticorps Rbbp8, anticorps rbbp8.L, anticorps rbbp8
- Poids moléculaire
- 120 kDa
- ID gène
- 5932
- Pathways
- Cycle Cellulaire, Réparation de l'ADN
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