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MLL/KMT2A anticorps (AA 2829-2883)

MLL Reactivité: Humain, Souris WB, ChIP, ICC, ChIP-seq, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2668494
  • Antigène Voir toutes MLL/KMT2A (MLL) Anticorps
    MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
    Épitope
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2829-2883
    Reactivité
    • 23
    • 11
    • 9
    Humain, Souris
    Hôte
    • 18
    • 5
    Lapin
    Clonalité
    • 19
    • 4
    Polyclonal
    Conjugué
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MLL/KMT2A est non-conjugé
    Application
    • 10
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq), Immunofluorescence (IF)
    Purification
    Protein A Chromatography
    Immunogène
    This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 2829-2883 of human MLL.
    Isotype
    IgG
    Top Product
    Discover our top product MLL Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1 μg/μL
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Stock
    -20 °C
    Stockage commentaire
    Antibodies in solution can be stored at -20 °C for 2 years.
    Date de péremption
    6 months
  • Kühn, Löscher, Marschalek: "The IRX1/HOXA connection: insights into a novel t(4;11)- specific cancer mechanism." dans: Oncotarget, Vol. 7, Issue 23, pp. 35341-52, (2016) (PubMed).

    Kang, Piao, Ryu, Kang, Chang, Keum, Hyun: "Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells." dans: Oncotarget, Vol. 7, Issue 26, pp. 40594-40620, (2016) (PubMed).

    Ahmad, Katryniok, Scholz, Merkens, Löscher, Marschalek, Steinhilber: "Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL." dans: Oncogenesis, Vol. 3, pp. e127, (2014) (PubMed).

    Pradeepa, Grimes, Taylor, Sutherland, Bickmore: "Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins." dans: Nucleic acids research, Vol. 42, Issue 14, pp. 9021-32, (2014) (PubMed).

    Wilkinson, Ballabio, Geng, North, Tapia, Kerry, Biswas, Roeder, Allis, Melnick, de Bruijn, Milne: "RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction." dans: Cell reports, Vol. 3, Issue 1, pp. 116-27, (2013) (PubMed).

  • Antigène
    MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
    Autre désignation
    MLL / HRX (MLL Produits)
    Synonymes
    anticorps ALL-1, anticorps CXXC7, anticorps HRX, anticorps HTRX1, anticorps MLL, anticorps MLL/GAS7, anticorps MLL1A, anticorps TET1-MLL, anticorps TRX1, anticorps WDSTS, anticorps 6430520K01, anticorps All1, anticorps Cxxc7, anticorps Mll, anticorps Mll1, anticorps mKIAA4050, anticorps lysine methyltransferase 2A, anticorps lysine (K)-specific methyltransferase 2A, anticorps KMT2A, anticorps Kmt2a
    Poids moléculaire
    180 kDa
    ID gène
    4297
    Pathways
    L'effet Warburg
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