EZH2 anticorps (AA 1-370)
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- Antigène Voir toutes EZH2 Anticorps
- EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
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Épitope
- AA 1-370
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EZH2 est non-conjugé
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Application
- Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
- Purification
- None
- Immunogène
- This EZH2 antibody was raised against a recombinant fusion protein corresponding to amino acids 1-370 of mouse EZH2.
- Top Product
- Discover our top product EZH2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Stock
- -20 °C
- Stockage commentaire
- Antibodies in solution can be stored at -20 °C for 2 years.
- Date de péremption
- 6 months
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Loss of BAP1 function leads to EZH2-dependent transformation. ..." dans: Nature medicine, Vol. 21, Issue 11, pp. 1344-9, (2015) (PubMed).
: "Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. ..." dans: Molecular cancer therapeutics, Vol. 13, Issue 4, pp. 842-54, (2014) (PubMed).
: "Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations. ..." dans: The Journal of clinical investigation, Vol. 123, Issue 11, pp. 4627-40, (2014) (PubMed).
: "Retinoic acid controls body axis extension by directly repressing Fgf8 transcription." dans: Development (Cambridge, England), Vol. 141, Issue 15, pp. 2972-7, (2014) (PubMed).
: "Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5012-22, (2014) (PubMed).
: "Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas. ..." dans: Cancer cell, Vol. 24, Issue 5, pp. 660-72, (2013) (PubMed).
: "A transcriptional repressor co-regulatory network governing androgen response in prostate cancers." dans: The EMBO journal, Vol. 31, Issue 12, pp. 2810-23, (2012) (PubMed).
: "ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression." dans: Cancer cell, Vol. 22, Issue 2, pp. 180-93, (2012) (PubMed).
: "Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT." dans: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 5, pp. 993-1006, (2010) (PubMed).
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Loss of BAP1 function leads to EZH2-dependent transformation. ..." dans: Nature medicine, Vol. 21, Issue 11, pp. 1344-9, (2015) (PubMed).
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- Antigène
- EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
- Autre désignation
- EZH2 (EZH2 Produits)
- Poids moléculaire
- 96 kDa
- ID gène
- 2146
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
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